ABSTRACT DIFFERENT DOSES OF DEXMEDETOMIDINE AS AN ADJUVENT

ABSTRACT

BACKGROUND

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 IN ORDER TO INCREASE THE DURATION OF ACTION OF
SPINAL ANAESTHESIA, INTRATHECAL DEXMEDETOMIDINE IS ADDED AS ADJUVENT TO LOCAL
ANAESTHETICS FOR ABDOMINAL HYSTERECTOMY SURGERIES .NOT MUCH STUDIES HAVE BEEN
DONE TO EVALUATE DIFFERENT DOSES OF DEXMEDETOMIDINE AS A ADJUVENT.

AIM

TO
ACCESS THE EFFICACY  AND SAFETY OF TWO
DIFFERENT DOSES  OF DEXMEDETOMIDINE AS AN
ADJUVENT TO ISOBARIC ROPIVACAINE,INTRATHECALLY 
ON ABDOMINAL HYSTERECTOMY SURGERIES.

MATERIALS
AND METHODS

SIXTY
PATIENTS SCHEDULED FOR HYSTERECTOMY SURGERIES ARE RANDOMIZED INTO TWO GROUPS A
AND B.GROUP A RECEIVED 2.6ML OF ISOBARIC ROPIVACAINE AND 10µ DEXMEDETOMIDINE.GROUP
B RECEIVED 2.6ML OF ISOBARIC ROIVACAINE AND 15 µ DEXMEDETOMIDINE.

RESULTS

THE
SENSORY BLOCKADE AND MOTOR BLOCKAGE ONSET TIME OF GROUP A IS (4.48±031MIN )
AND( 6.1±0.28 MIN) RESPECTIVELLY.THIS IS STATISTICALLY SIGNIFICANT(P120 KG) ,HEIGHT 30% OF THE
BASELINE VALUE OR SYSTOLIC BLOOD PRESSURE